SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression

Cell Biochemistry & Function, Biochemistry Journal

Molecular mechanisms involved in pathogenicity of SARS-CoV-2: Immune evasion and implications for therapeutic strategies - ScienceDirect

Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses - ScienceDirect

Novel COVID-19 (SARS-CoV-2) Infection Induced Cytokine Storm

Research, Catherine Blish Lab

Natural killer cells associated with SARS-CoV-2 viral RNA shedding, antibody response and mortality in COVID-19 patients, Experimental Hematology & Oncology

Harnessing Natural Killer Cell-Mediated Innate Immune Responses for Cancer Treatment: Advances and Challenges

Harnessing the Power of Natural Killer Cells for Cancer Immunotherapy

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

Infographic: How SARS-CoV-2 Immune Responses May Differ by Sex