Android 16 (Character) - Giant Bomb

Android 16 is an android created by Dr. Gero to kill Goku. He was considered a failure and remained deactivated until Android 17 killed Gero and activated him.

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Android 1617 (Character) - Giant Bomb

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Can someone explain what the deal is with 21 is to me? Is 16 her son? Why does she have a majin form? Was she created be Gero? I'm very confused